DR. BHAVYA GORIMANIPALLI

Prof.ROHIT SHETTY, Dr.POOJA KHAMAR

Abstract

Purpose: To assess the stability of keratoconus (KC) in thin corneas (<400µ) post collagen crosslinking (CXL) using in-vivo collagen imaging with polarization sensitive optical coherence tomography(PS-OCT) Methods: 30 eyes of 30 patients with progressive KC and thinnest corneal thickness < 400µ underwent (CXL) with customized UV fluence calculated by the NXT – UVA online calculator. Pre-operative and post-operative (36 months) topography and PS-OCT scans of 10 mm diameter were captured, and corneal fibril distribution images were generated using phase retardation (PR) maps. Eyes were imaged 3 times for repeatability Results: Mean keratometry reduced from 55.32±3.8 preoperatively to 53.02±3.77 at postoperative 36 months. PR maps showed stability in the birefringence till 12 months following the CXL Conclusions: The current study shows that CXL with customized UV fluence (NXT-UVA calculator) is safe and effective in halting the progression of KC using in-vivo collagen imaging by PS-OCT

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