Dr. RIA BATRA

Dr.Neelima Mehrotra, DR. SAKSHI SINGH, Dr. SARA RIZVI

Abstract

Aim

To evaluate the efficacy of topical interferon (IFN) in patients developing pseudophakic cystoid macular edema

Material & Method

Prospective, interventional study on patients having CME after cataract surgery. Patients consenting for the study were advised to use topical IFN drops 4 times/day (1MIU/ml)

OCT was done at the baseline and on each follow-up

Result

13 eyes of 13 patients diagnosed with P‑CME were studied. Mean central macular Thickness (CMT) on OCT at the presentation (n = 13) CMT on OCT at the presentation (n = 13) and at 4 weeks post topical IFN therapy (n = 10) was 557 µm (range: 352–705 µm) and 353 µm (range: 240–394 µm), respectively. All eyes had PCR, 9 patients had regular follow‑up for 6 months. The mean duration of complete resolution of CME was 6 weeks in these patients. Relapse was seen in 2 patients

No ocular or systemic side effects related to the topical IFN therapy were noted

Conclusion

Topical IFN therapy can be an effective choice of treatment for CME

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