Dr. RITICA MUKHERJI

Prof.ROHIT SHETTY, Dr.POOJA KHAMAR, DR. DIVYA TRIVEDI

Abstract

Objective: Laser-based cross-linking (CXL) has advanced from corneal wavefront-guided (CW) treatment to ocular wavefront-guided (OW) and topo-guided removal of epithelium in keratoconus (TREK). We designed an algorithm to choose the right laser-based CXL in keratoconus (KC). Methods: Based on corneal curvature, thinnest corneal thickness, corneal and internal aberrations, stromal ablation; patients were divided into CW (35 eyes), OW (123 eyes), TREK (48 eyes) groups. Visual acuity, keratometry, corneal, internal and total ocular aberrations, assessed pre-operatively and post-operatively at 1, 6 months. Result: BCVA, SEQ, keratometry, defocus, coma, SA reduced significantly (p<0.05) in CW and TREK groups. OW group had higher decrease in keratometry, defocus, SA (p<0.001). TREK and OW group had lesser tissue ablation (p<0.001) vis-a-vis CW group. Conclusion: This algorithm can be used to customize laser based CXL for ectasia, optimizing tissue ablation and enhancing visual outcomes.

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