Dr. Mangala P

DR. REVATHI RAJARAMAN, Dr.ARJUN VELAYUDHAN NAIR

Abstract

To report successful medical management of Pythium insidiosum keratitis using an combination of minocycline, along with linezolid and oral minocycline. An interventional case seriesof 4 cases, clinically suspected, then microbiologically and confocal proven pythium keratitis, who had 1% minocycline and 0.2%linezolidalong with oral 100 mg minocyclineBD was given ,These cases were followed up in regular intervals.Resolution manifested by decreasein number density of tentacular extensions with a reduction in the cellularity of surrounding stroma. On follow-up, a formation of peripheral guttering surrounding the infiltrate was observed along deep vascularization. Medical treatment resulted in the resolution of infection in all 4 cases of witha duration of 3 months. cases healed with scarring without surgical intervention and drastic complications..The patients were closely monitored for the development of a limbal and deep stromal extension of infection during regular follow-ups.

Full Text