DR. ARVIND KUMAR MORYA

DR. MANISHA RATHI, DR. INDER M. RUSTAGI, DR. PRIYA SISODIYA

Abstract

Background: Axenfeld-Reiger Syndrome (ARS) is a rare cause of congenital glaucoma&may result in loss of vision. ARS is mostly autosomal dominant in nature characterized by developmental abnormalities in the angle of anterior chamber&iris of the eye&structural abnormalities in the body.

Study Design : Prospective interventional

Methods:Patients presenting to Ophthalmology OPD from March2018 to June2022actively screened to search for the salient features ofARS.5 patients had clinical characteristics suggestive ofARS. Patients then evaluated for demographic&clinical characterization as well as management. Family members of patients actively searched.4 cases diagnosed as a result of search.

Results:8out of10patients with positive clinical signs were symptomatic&found to have glaucoma.1patient had limbal stem cell deficiency&1had vernal keratoconjunctivitis.

Conclusion: Clinical characterization of ARS is important for making a definitive diagnosis and determining the prognosis.