DR. NINAN P. JACOB

DR. NIROJ KUMAR SAHOO, Dr.MUDIT TYAGI, Dr.Jay Kumar Chhablani

Abstract

Objective:To evaluate the correlation between RPE thickness and choroidal thickness using swept source OCT in cases of acute VKH and to assess RPE reflectivity and to assess their role as biomarkers of inflammation in acute VKH

Methods:A retrospective observational study of 55 eyes of 29 patients of acute VKH was done using SS-OCT. RPE, inner and total choroidal thickness before and after treatment, RPE reflectivity before and after treatment was analysed using image J software.

Results: There was a significant increase in RPE reflectivity following treatment (p=0.001). Also, there was a significant decrease in RPE thickness following treatment (p=0.0004), with RPE thickness correlating with inner and total choroidal thickness in the acute phase.

Conclusion:RPE thickness and RPE reflectivity can be used as markers of acute inflammation in VKH when the choroidal thickness cannot be measured. Also, there is an inverse relation between RPE reflectivity and thickness in VKH.

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