DR. AYUSHI SARDANA

Dr. KAMALJEET SINGH, Dr.ARTI SINGH, DR. SHWETA GUPTA

Abstract

Purpose – To study correlation of OCT biomarker PROS and CMT in Diabetic Macular Oedema (DMO) treated with intravitreal anti-VEGF

Methodology– Prospective, interventional study done in a Tertiary Care Hospital for 8 months. 20 patients(pts.) were diagnosed with DMO after complete Ophthalmic and routine laboratory examination. OCT biomarker PROS (Photoreceptor Outer Segment) length was taken as vertical extent from IS/OS junction to RPE in the 1 mm foveal area. Pts were assessed pre-op ,at 1 month(mnth), 2 mnth, & 3mnth post-op.

Findings- 4 pts (20%) had pre op PROS <=35 um, out of whom in 1 pt. (5%), CMT decreased to <= 350 um at 2 mnth and in 3 pts(15%) at 3 mnth. 12 pts(60%) had PROS of 36 to <=45um, out of whom 8pts(40%) showed a decrease of CMT at 1 mnth, 3 pts(15%) at 2 mnth and 1 pt (5%) at 3 mnth. 4 pts (20%) had PROS >45 um, out of whom 3pts(15%) showed a decrease of CMT at 1 mnth and 1 pt(5%) at 2 mnths.

Result- PROS is a reliable prognostic OCT biomarker in patients of DMO.

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