DR. SAVITRI KUMARI

Prof.ROHIT SHETTY, Dr.POOJA KHAMAR, Dr. RITICA MUKHERJI

Abstract

Purpose:To analyse long-term safety & efficacy of Topography-guided Removal of Epithelium in Keratoconus followed by collagen cross-linking (CXL).

Methods:78 eyes with minimum corneal thickness <420um but >400um, underwent TREK. A decentered ablation of 70um was done at steepest anterior curvature followed by CXL. Post-operative UCVA,BCVA, topography and aberration profile were analysed at 5years. Collagen orientation was studied pre and post-operatively by Polarisation-Sensitive Optical Coherence Tomography (PS-OCT).

Results:At post-op 5 year, there was a significant increase in UCVA (0.73±0.32 to 0.59± 0.33 logMAR, p=0.0006) and BCVA (0.18±0.13 to 0.12±0.12 logMAR,p=0.0034) respectively. Mean keratometry decreased significantly from 49.64±0.45D to 47.63±0.46D(p<0.001). The PSOCT maps showed strengthening of collagen fibrils post-operatively. Conclusions:TREK, being a tissue saving procedure, is a safe and effective alternative to topo-guided PRK with CXL in the long term.

Full Text