Dr. NITHIN KESHAV SRINIVASAN

DR. NAVEEN KESHAV S

Abstract

43 patients (86 eyes) diagnosed as VKH and undergone OCT Angiography (OCTA) were recruited in the study. All patients underwent serial EDI OCT and ICGA. Area of flow voids, flow void number and size of flow voids were calculated using MATLAB. 14% patients in the acute phase of VKH and 86% patients in the chronic phase. Mean sub foveal choroidal thickness (SFCT) was 308.2µ. Positive association between presence of flow voids in OCTA and presence of hypo dots in IGA. Odds of detecting a flow void in OCTA in an ICGA active disease is 6 (95% CI= 0.32-112.26). Positive correlation is seen between average RNFL thickness and area of flow voids (Pearson correlation coefficient 0.41, p-value 0.001). AUC value between the flow void number and hypo dots in ICGA is 0.772 (p value 0.01) suggesting OCTA has good specificity in diagnosing hypocyanescent dots in ICGA (Gold Standard). OCTA can be a useful prognostic tool in VKH and help in avoiding multiple ICGA during monitoring the disease.

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