DR. SHREOSHEE GHOSH

DR. TANIA RAY (BHADRA)

Abstract

OBJECTIVE: To compare the efficacy of latanoprost (0.005%) with netarsudil (0.02%) in IOP reduction in ocular hypertension.METHODOLOGY: This is an interventional double blinded study in which patients were allocated between two groups, one receiving eye drop latanoprost(0.005%) and the other receiving eye drop netarsudil(0.02%)everyday in one eye and a placebo drug in the other. IOP was measured after 6 weeks. Follow up was for 18 months. RESULTS: the mean IOP of the latanoprost group was 25.4±5.11mm Hg before and 20.2±3.58mm Hg after drug instillation (20% reduction noted) after 6 weeks. In the netarsudil group IOP was 24.46±2.96mm Hg before and 12.92±3.42mm Hg after drug instillation (42% reduction noted) after 6 weeks. Over 18 months, IOP was maintained and there was no change in the vertical cup disc ratio and the visual fields of the patients of the netarsudil group.CONCLUSION: netarsudil is a better drug in terms of efficacy as compared to latanoprost in ocular hypertension