Dr. MODHWADIA JAYESH D.

, Dr. SHREYA SHAH, Dr.MEHUL SHAH, DR. SANJRI MALHOTRA

Abstract

INTRODUCTION: A POPULATION BASED STUDY FOUND INCIDENCE RATE OF 22 PER MILLION PERSON YEARS FOR MYASTHENIA GRAVIS, WITH OCULAR & MYASTHENIA GRAVIS OCCURRING AT A RATE OF 11.3 PER MILLION PERSON YEARS. IN PEDIATRIC POPULATION INCIDENCE IS ESTIMATED TO BE BETWEEN 1.0 & 5.0 CASES PER MILLION PERSON YEARS.

METHOD:THIS VIDEO IS A CASE OF 4 YEAR WITH DROOPING OF LIDS & DECREASE OCULAR MOVEMENTS IN BOTH EYES,WORSENING BY THE END OF DAY SINCE 2 YEARS.PATIENT HAD COMPENSATING HEAD POSITION WITH CHIN ELEVATION,PTOSIS & RESTRICTED OCULAR MOVEMENTS IN ALL GAZES,ANTERIOR & POSTERIOR SEGMENT WERE NORMAL.CLINICALLY DIAGNOSIS OF OCULAR VARIANT WAS MADE.PHARMACOLOGICAL ANALYSIS WITH 0.5-MG NEOSTIGMINE RESULTED IN MARKED IMPROVEMENT IN PTOSIS & EYE MOVEMENTS OF BOTH EYES.

ANTI-ACH ANTIBODIES WERE IN NORMAL RANGE.PATIENT WAS STARTED ON PYRIDOSTIGMINE 30MG TDS RESULTED IN SIGNIFICANT IMPROVEMENT

CONCLUSION:IT IS A RARE DISEASE IN PEDIATRIC POPULATION.TREATMENT IN CHILDREN IS SIMILAR TO THAT OF ADULTS.