DR. SUKRITI GUPTA

MRS.SARITA AGGARWAL, DR. SHIKHA, DR.SOMESH RANJAN

Abstract

Aim:

To describe the efficacy & safety

of Ologen implant over Mitomycin C in trabeculectomy.

Method:

Various studies compared ologen implant with mitomycin c in trabeculectomy.

Efficacy measures selected were:

1. Post OP IOP reduction

2. Reduction in Glaucoma medications

3. Adverse effects

Results:

Benefits of ologen implant over MMC are:

1. Prevention of scar formation & hypotony.

2. Normal subconjunctival stroma formation.

3. Facilitates poor wound healing & physiological functional bleb formation.

4. It’s fully biodegradable.

5. Non teratogenic.

6. No prior preparation required & saves operation time.

Conclusion:

The use of ologen implant promises comparable IOP reduction after trabeculectomy with lower risk profile over anti-metabolites.

A study done in 2014 used this in the management of glaucoma in an unusual case of Axenfeld-Reiger syndrome.