Dr. SHAIFALI CHAHAR

Dr.Deepthi Elizabeth Kurian, Dr. SHAIFALI CHAHAR, DR. KAUSTUBH MULAY, Dr. SANTOSH G. HONAVAR

Abstract

Purpose: To describe the clinical profile and identify risk factors for local recurrence (LR) and metastasis in sebaceous gland carcinoma (SGC) of the eyelid. Methods: A retrospective observational study was done of 183 consecutive patients, histopathologically diagnosed with SGC, operated at a tertiary eye hospital in South India. Data was obtained from out-patient records. Results: Mean age was 57.3 ± 13.3 years and 53.6% were females. Mean follow-up duration was 25.3 ± 27.2 months. The incidence rate of LR and metastasis was found to be 0.12 and 0.04 per person per year respectively. On logistic regression, independent risk factors for LR were lymphovascular invasion (OR 3.2, 95% CI 0.9 – 10.7) and pagetoid spread (OR 1.5, 95% CI 0.5 – 4.1), whereas those for metastasis was size more than 20mm (OR 3.3, 95% CI 0.82- 13.79). Conclusions: Risk factors for LR and metastasis of SGC were identified. Standardised surgical approach could be pivotal in optimising outcome.

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